1. Unique strain resource library

After over 20 years of systematic collection and construction, we have established the largest tropical rainforest-characterized Bacillus resource bank both domestically and internationally, preserving 300,000 Bacillus strains, including over 20 patented strains with promising applications. This unique treasure trove of microbial resources serves as the foundation for our continuous exploration of novel functional genes.

For instance, we have identified over 200 wild strains exhibiting varying mosquito-killing activities, among which the patented strains HSY91, HSY56, HSY354, and HSY22 have demonstrated nanogram-level mosquito-killing activity. Leveraging these high-quality strains, we can develop bio-based mosquito repellents with proprietary intellectual property rights, offering efficient solutions for vector control and boasting vast market prospects.

2. A pragmatic and efficient gene mining platform

We have established an efficient platform for gene discovery and functional verification. To date, we have completed whole-genome sequencing for over a thousand bacterial strains and identified and cloned more than 1,500 insecticidal protein genes with full independent intellectual property rights. Our platform integrates multi-dimensional bioinformatics analysis methods, including BLAST alignment based on protein homology, sequence composition (TNF) analysis based on neural network algorithms, and self-developed machine learning models, enabling efficient screening and identification of novel insecticidal protein genes. Building on our strengths in gene resources against lepidopteran and coleopteran pests, we are focusing on breaking through industry shortcomings in gene resources against hemipteran pests (such as aphids, red spider mites, whiteflies, etc.) and crop nematodes.